Structure of PDB 6bba Chain C Binding Site BS02

Receptor Information
>6bba Chain C (length=189) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SLIPIVVEQTGRGERAYDIYSRLLRERIVCVMGPIDDSVASLVIAQLLFL
QSESNKKPIHMYINSPGGVVTAGLAIYDTMQYILNPICTWCVGQAASMGS
LLLAAGTPGMRHSLPNSRIMIHQPSATDIAIQAEEIMKLKKQLYNIYAKH
TKQSLQVIESAMERDRYMSPMEAQEFGILDKVLVHPPQD
Ligand information
Receptor-Ligand Complex Structure
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PDB6bba Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.
Resolution2.796 Å
Binding residue
(original residue number in PDB)		L147 T178 Y181
Binding residue
(residue number reindexed from 1)		L48 T79 Y82
Enzymatic activity
Enzyme Commision number 3.4.21.92: endopeptidase Clp.
Gene Ontology
Molecular Function
GO:0004176 ATP-dependent peptidase activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:6bba, PDBe:6bba, PDBj:6bba
PDBsum6bba
PubMed30126533
UniProtQ16740|CLPP_HUMAN ATP-dependent Clp protease proteolytic subunit, mitochondrial (Gene Name=CLPP)

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