Structure of PDB 5wvo Chain C Binding Site BS02

Receptor Information
>5wvo Chain C (length=232) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CIQCGLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESYEALPQHKLTC
FSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSLEGGVNGKNLG
PINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIFGLMQEKIYIS
KIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDSLLRHAQFVVE
QVESYDEAGDSDEQPIFLTPCMRDLIKLAGVT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain5wvo Chain C Residue 701 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB5wvo Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance
Resolution1.997 Å
Binding residue
(original residue number in PDB)		C353 C356 C414 H418
Binding residue
(residue number reindexed from 1)		C1 C4 C55 H59
Annotation score1
Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
External links
PDB RCSB:5wvo, PDBe:5wvo, PDBj:5wvo
PDBsum5wvo
PubMed29053958
UniProtP26358|DNMT1_HUMAN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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