Structure of PDB 5vvx Chain C Binding Site BS02
Receptor Information
>5vvx Chain C (length=431) Species:
9606
(Homo sapiens) [
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HFLCGVVEGFYGRPWVMEQRKELFRRLQKWELNTYLYAPKDDYKHRMFWR
EMYSVEEAEQLMTLISAAREYEIEFIYAISPGLDITFSNPKEVSTLKRKL
DQVSQFGCRSFALLFDNIDHNMCAADKEVFSSFAHAQVSITNEIYQYLGE
PETFLFCPTEYCGTFCYPNVSQSPYLRTVGEKLLPGIEVLWTGPKVVSKE
IPVESIEEVSKIIKRAPVIWDNIHANDYDQKRLFLGPYKGRSTELIPRLK
GVLTNPNCEFEANYVAIHTLATWYKSNMLYSPQMALKLALTEWLQEFSVT
LEDLQLLADLFYLPYEHGPKGAQMLREFQWLRANSSVVEKIEEWRSRAAK
FEEMCGLVMGMFTRLSNCANRTILYDMYSYVWDIKSIMSMVKSFVQWLGC
RSHSSAQFLIGDQEPWAFRGGLAGEFQRLLP
Ligand information
>5vvx Chain D (length=4) Species:
9606
(Homo sapiens) [
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SRVT
Receptor-Ligand Complex Structure
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PDB
5vvx
Structural insights into the substrate binding adaptability and specificity of human O-GlcNAcase.
Resolution
2.9 Å
Binding residue
(original residue number in PDB)
N175 V255 R290 Y569
Binding residue
(residue number reindexed from 1)
N117 V197 R232 Y315
Enzymatic activity
Enzyme Commision number
3.2.1.169
: protein O-GlcNAcase.
External links
PDB
RCSB:5vvx
,
PDBe:5vvx
,
PDBj:5vvx
PDBsum
5vvx
PubMed
28939839
UniProt
O60502
|OGA_HUMAN Protein O-GlcNAcase (Gene Name=OGA)
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