Structure of PDB 5vvl Chain C Binding Site BS02

Receptor Information
>5vvl Chain C (length=267) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VSMIFLQYGQIDVIDGAFVLIDKTGIRTHIPVGSVACIMLEPGTRVSHAA
VRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQAKLALDEDLRLK
VVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYALLAKQYGVTWNGRR
YDPKDWEKGDTINQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLS
FVYDIADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKL
IPLIEDVLAAGEIQPPA
Ligand information
>5vvl Chain J (length=41) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cactggtggtcgccgcggttggaacactctaagatattaga
Receptor-Ligand Complex Structure
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PDB5vvl Structures of the CRISPR genome integration complex.
Resolution3.31 Å
Binding residue
(original residue number in PDB)		R132 E135 Q136 R138 G139 E141 G142 S143 V145 R146 Y149 G162 R164
Binding residue
(residue number reindexed from 1)		R118 E121 Q122 R124 G125 E127 G128 S129 V131 R132 Y135 G148 R150
Enzymatic activity
Enzyme Commision number 3.1.-.-
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0004520 DNA endonuclease activity
GO:0005515 protein binding
GO:0008821 crossover junction DNA endonuclease activity
GO:0017108 5'-flap endonuclease activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006281 DNA repair
GO:0006974 DNA damage response
GO:0043571 maintenance of CRISPR repeat elements
GO:0051607 defense response to virus
GO:0099048 CRISPR-cas system
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vvl, PDBe:5vvl, PDBj:5vvl
PDBsum5vvl
PubMed28729350
UniProtQ46896|CAS1_ECOLI CRISPR-associated endonuclease Cas1 (Gene Name=ygbT)

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