Structure of PDB 5v5x Chain C Binding Site BS02

Receptor Information

>5v5x Chain C (length=415) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PVFSQDVYRVRLPEDLPPGTTVLRLKAAEFTYSFLGVANKAQFSLDPITG
DIVTRQSLDFEEVEQYTIDVEAKDRGSLSSQCKVIIEVLDENDNRPEIII
TSLSDQISEDSPSGTVVALFKVRDRDSGENAEVMCSLSGNNPFKIHSSSN
NYYKLVTDSILDREQTPGYNVTITATDRGKPPLSSSTTITLNVADVNDNA
PVFQQQAYLINVAENNQPGTSITQVKAWDPDVGSNGLVSYSIIASDLEPK
ALSSFVSVNQDSGVVYAQRAFDHEQIRSFQLTLQARDQGSPALSANVSMR
VLVDDRNDNAPRVLYPTLEPDGSALFDMVPRAAEPGYLVTKVVAVDADSG
HNAWLSYHVLQASDPGLFSLGLRTGEVRTARALSDKDAARQRLLVAVRDG
GQPPLSATATLLLVF

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

5v5x Chain C Residue 702 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	5v5x Protocadherin cis-dimer architecture and recognition unit diversity.
Resolution	3.5 Å
Binding residue (original residue number in PDB)	E223 E278 D307 E308 D310 D343
Binding residue (residue number reindexed from 1)	E14 E61 D90 E91 D93 D126
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Molecular Function
GO:0005509	calcium ion binding

	Biological Process
GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane

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Cellular Component

External links

PDB	RCSB:5v5x, PDBe:5v5x, PDBj:5v5x
PDBsum	5v5x
PubMed	29087338
UniProt	Q91XX3

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