Structure of PDB 5uly Chain C Binding Site BS02

Receptor Information
>5uly Chain C (length=221) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TFKHESYYATVNELTPVGTTIFTGFSGDNGIEYVIQYNPDDPTSNDTFEI
PLMLTGNIVLRKRLNYEDKTRYFVIIQANTTTTTLTVDVLDGDDLGPMFL
PCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQDRNIQPP
SDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIK
AEQDNGHPLPAFAGLHIEILD
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain5uly Chain C Residue 1002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB5uly Structural determinants of protocadherin-15 mechanics and function in hearing and balance perception.
Resolution2.64 Å
Binding residue
(original residue number in PDB)		D238 L240 D287 D289 Q348
Binding residue
(residue number reindexed from 1)		D93 L95 D142 D144 Q203
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5uly, PDBe:5uly, PDBj:5uly
PDBsum5uly
PubMed32963095
UniProtQ96QU1|PCD15_HUMAN Protocadherin-15 (Gene Name=PCDH15)

[Back to BioLiP]