Structure of PDB 5njj Chain C Binding Site BS02
Receptor Information
>5njj Chain C (length=141) Species:
9606
(Homo sapiens) [
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DEEGVRTGKCSFPVKYLGHVEVDESRGMHICEDAVKRLKAERKFFKGFFG
KTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAF
SYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLER
Ligand information
>5njj Chain H (length=7) Species:
9606
(Homo sapiens) [
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AYIGPYL
Receptor-Ligand Complex Structure
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PDB
5njj
A Numb-Mdm2 fuzzy complex reveals an isoform-specific involvement of Numb in breast cancer.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
R53 G159 A163 L166
Binding residue
(residue number reindexed from 1)
R26 G132 A136 L139
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5njj
,
PDBe:5njj
,
PDBj:5njj
PDBsum
5njj
PubMed
29269425
UniProt
P49757
|NUMB_HUMAN Protein numb homolog (Gene Name=NUMB)
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