Structure of PDB 5nc7 Chain C Binding Site BS02
Receptor Information
>5nc7 Chain C (length=110) Species:
9606
(Homo sapiens) [
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SEQSICQARAAVMVYDDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVVGR
KIQDHQVVINCAIPKGLKYNQATQTFHQWRDARQVYGLNFGSKEDANVFA
SAMMHALEVL
Ligand information
>5nc7 Chain Y (length=4) Species:
1639
(Listeria monocytogenes) [
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PPPP
Receptor-Ligand Complex Structure
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PDB
5nc7
Designed nanomolar small-molecule inhibitors of Ena/VASP EVH1 interaction impair invasion and extravasation of breast cancer cells.
Resolution
2.7 Å
Binding residue
(original residue number in PDB)
Y38 R47 R51
Binding residue
(residue number reindexed from 1)
Y37 R46 R50
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:5nc7
,
PDBe:5nc7
,
PDBj:5nc7
PDBsum
5nc7
PubMed
33184177
UniProt
Q8N8S7
|ENAH_HUMAN Protein enabled homolog (Gene Name=ENAH)
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