Structure of PDB 5lak Chain C Binding Site BS02

Receptor Information
>5lak Chain C (length=303) Species: 1041929 (Cavally virus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SAASNPSISHIVLEMPVAINPLIKYTTRTSVSSLRGAVVNGYIYIQRHLF
GSKKQEFEACYNNGKGLLNCKNLERSKYDIDSAELIGTLIRIPLHDKHSI
PHISIHPDPLSYNGPVTLYLSRYDTNKDVLCVHTGFMSEGHHDIKTVFGD
CGGMLFDPKGRLLGLHCAGSDDVVFMDTTTGKSNIWTSYKLQHPSEIMIT
LNNEINLPNPANYDFETTKVVYQHPLRNVCATLETLQHLTNKTNAKLPYD
SRLLSDFNITAEQYNQYGYYIDYNNFVNNFNRYTTTTIGTKSFETCIKYG
LMD
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5lak Structural basis for catalysis and substrate specificity of a 3C-like cysteine protease from a mosquito mesonivirus.
Resolution2.299 Å
Binding residue
(original residue number in PDB)		H48 T148 F150 G151 C153 H168 C169 A170 G171 S172 D173 Y215 D216 E218 T219 T220 K221
Binding residue
(residue number reindexed from 1)		H48 T146 F148 G149 C151 H166 C167 A168 G169 S170 D171 Y213 D214 E216 T217 T218 K219
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004197 cysteine-type endopeptidase activity

View graph for
Molecular Function
External links
PDB RCSB:5lak, PDBe:5lak, PDBj:5lak
PDBsum5lak
PubMed31078932
UniProtF8RL29|R1AB_AMV79 Replicase polyprotein 1ab (Gene Name=pp1ab)

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