Structure of PDB 5ks8 Chain C Binding Site BS02

Receptor Information
>5ks8 Chain C (length=603) Species: 265072 (Methylobacillus flagellatus KT) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KVHVTDVVLRDGHQSLIATRMRTDDMLPICSKLDAVGYWSLEAWGGATFD
ACVRYLREDPWERLKKLRKALPNSRLQMLLRGQNLLGYRHYSDDVVRAFV
QKSADNGIDVFRIFDAMNDLRNLKVSIESVKAVGKHAEGTISYTTSPVHD
IPYFVNLAKELESFGCDTIAIKDMASLLTPQVTGDLVKALREAVSLPIHL
HAHATSGLASMSIQRAVDNGVAIVDGCISSFAEGASLPATESIVAALKGT
EYDTGLDIGLLQEISAYFREVRKKYWQFESEFTGVDTRVLVNQVPGGMIS
NLSNQLKEQGALDRMDAVLDEIPRVREDLGYPPLVTPTSQIVGTQAVLNV
MTGARYKSVTNEVKNYLLGHYGKAPSTVNPDVRNLAVGNAQVIECRPADL
LTAEMEKLRNEVEGLAASAADVLTYAMFPDLAKTFLQERNAGSLKPEPLL
DKEAVTSRESHSRFAPTEFNVTLHGETFHIKLTGSGHHGEEQRPFYVSVD
GVTEEVVVEILNEAKRKASSAASSGRPRPTHAGCVTTAMPGTIVDVKVNV
GDKVSAGDAVLVIEAMKMENEIQASKSGVVVAINVKKGDSVTPDEALLEI
QPD
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain5ks8 Chain C Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ks8 A distinct holoenzyme organization for two-subunit pyruvate carboxylase.
Resolution3.01 Å
Binding residue
(original residue number in PDB)		D13 K174 H203 H205
Binding residue
(residue number reindexed from 1)		D11 K172 H201 H203
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) D13 D117 K174 H203 H205
Catalytic site (residue number reindexed from 1) D11 D115 K172 H201 H203
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004736 pyruvate carboxylase activity
GO:0008948 oxaloacetate decarboxylase activity
GO:0046872 metal ion binding
Biological Process
GO:0006814 sodium ion transport

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5ks8, PDBe:5ks8, PDBj:5ks8
PDBsum5ks8
PubMed27708276
UniProtQ1H157

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