Structure of PDB 5ez0 Chain C Binding Site BS02
Receptor Information
>5ez0 Chain C (length=94) Species:
9606
(Homo sapiens) [
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PHDNLVLIRMKPDENGRFGFNVKGGYDQKMPVIVSRVAPGTPADLCVPRL
NEGDQVVLINGRDIAEHTHDQVVLFIKASCERHSGELMLLVRPN
Ligand information
>5ez0 Chain G (length=11) Species:
9606
(Homo sapiens) [
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SWARVSKETPL
Receptor-Ligand Complex Structure
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PDB
5ez0
Molecular Basis of the Interaction of the Human Protein Tyrosine Phosphatase Non-receptor Type 4 (PTPN4) with the Mitogen-activated Protein Kinase p38 gamma.
Resolution
2.35 Å
Binding residue
(original residue number in PDB)
R527 F528 G529 F530 N531 V532 K533 Q538 K539 M540 S545 H579 D580 V583
Binding residue
(residue number reindexed from 1)
R17 F18 G19 F20 N21 V22 K23 Q28 K29 M30 S35 H69 D70 V73
Enzymatic activity
Enzyme Commision number
3.1.3.48
: protein-tyrosine-phosphatase.
External links
PDB
RCSB:5ez0
,
PDBe:5ez0
,
PDBj:5ez0
PDBsum
5ez0
PubMed
27246854
UniProt
P29074
|PTN4_HUMAN Tyrosine-protein phosphatase non-receptor type 4 (Gene Name=PTPN4)
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