Structure of PDB 5d4d Chain C Binding Site BS02

Receptor Information
>5d4d Chain C (length=1108) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRE
TFPIEEGLVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTG
LIKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPG
RYIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQET
LARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAY
VYGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPT
LRYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVR
ERMLMSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHKRRI
SALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAAYAR
VDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNRIAA
ERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANRALM
GSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVDGNR
IVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLADGPA
SENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIERYEI
EARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVGRTS
FKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLRRGD
PGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVEDMPH
LPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFDGAK
EPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGKTPE
EQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHARST
GPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKSDDI
EGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDNPVD
IFEGLASK
Ligand information
Receptor-Ligand Complex Structure
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PDB5d4d The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		R243 P247 R266 R422
Binding residue
(residue number reindexed from 1)		R237 P241 R260 R412
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5d4d, PDBe:5d4d, PDBj:5d4d
PDBsum5d4d
PubMed27383794
UniProtQ8RQE9|RPOB_THET8 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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