Structure of PDB 4xnw Chain C Binding Site BS02

Receptor Information
>4xnw Chain C (length=350) Species: 1501,9606 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSFKCALTKTGFQFYYLPAVYILVFIIGFLGNSVAIWMFVFHMKPWSGIS
VYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDAMCKLQRFIFHVNLYG
SILFLTCISAHRYSGVVYPLKSLGRLKKKNAICISVLVWLIVVVAISPIL
FYSGTGVRKNKTITCYDTTSDEYLRSYFIYSMCTTVAMFCVPLVLILGCY
GLIVRALIYKMKKYTCTVCGYIYNPEDGDPDNGVNPGTDFKDIPDDWVCP
LCGVGKDQFEEVEEPLRRKSIYLVIIVLTVFAVSYIPFHVMKTMNLRARL
DFQTPAMCAFNDRVYATYQVTRGLASLNSCVNPILYFLAGDTFRRRLSRA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4xnw Chain C Residue 1102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4xnw Two disparate ligand-binding sites in the human P2Y1 receptor
Resolution2.7 Å
Binding residue
(original residue number in PDB)		C1006 C1009 C1039 C1042
Binding residue
(residue number reindexed from 1)		C216 C219 C249 C252
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0045028 G protein-coupled purinergic nucleotide receptor activity
GO:0046872 metal ion binding
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007200 phospholipase C-activating G protein-coupled receptor signaling pathway
GO:0030168 platelet activation
GO:0043448 alkane catabolic process
GO:0090075 relaxation of muscle
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4xnw, PDBe:4xnw, PDBj:4xnw
PDBsum4xnw
PubMed25822790
UniProtP00268|RUBR_CLOPA Rubredoxin;
P47900|P2RY1_HUMAN P2Y purinoceptor 1 (Gene Name=P2RY1)

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