Structure of PDB 4r2y Chain C Binding Site BS02

Receptor Information
>4r2y Chain C (length=65) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DENCGICRMAFNGCCPDCKVPGDDCPLVWGQCSHCFHMHCILKWLHAQQV
QQHCPMCRQEWKFKE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain4r2y Chain C Residue 102 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4r2y Mechanism of Polyubiquitination by Human Anaphase-Promoting Complex: RING Repurposing for Ubiquitin Chain Assembly.
Resolution1.755 Å
Binding residue
(original residue number in PDB)		C34 C37 C44 H58
Binding residue
(residue number reindexed from 1)		C15 C18 C25 H39
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0061630 ubiquitin protein ligase activity
GO:0097602 cullin family protein binding
Biological Process
GO:0031145 anaphase-promoting complex-dependent catabolic process
Cellular Component
GO:0005680 anaphase-promoting complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:4r2y, PDBe:4r2y, PDBj:4r2y
PDBsum4r2y
PubMed25306923
UniProtQ9NYG5|APC11_HUMAN Anaphase-promoting complex subunit 11 (Gene Name=ANAPC11)

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