Structure of PDB 4qmg Chain C Binding Site BS02

Receptor Information
>4qmg Chain C (length=306) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PTVQRGIIKMVLSGCAIIVRGQPRGGPPPERQINLSNIRAGNLARRADTP
DEPWAFPAREFLRKKLIGKEVCFTIENKTPQGREYGMIYLGKDTNGENIA
ESLVAEGLATRREGMRANNPEQNRLSECEEQAKAAKKGMWSEGNGSHTIR
DLKYTIENPRHFVDSHHQKPVNAIIEHVRDGSVVRALLLPDYYLVTVMLS
GIKCPTFRREAETPEPFAAEAKFFTESRLLQRDVQIILESCHNQNILGTI
LHPNGNITELLLKEGFARCVDWSIAVYTRGAEKLRAAERFAKERRLRIWR
DYVAPT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4qmg Structural Insights into the Tumor-Promoting Function of the MTDH-SND1 Complex.
Resolution2.701 Å
Binding residue
(original residue number in PDB)
P39 G42 P43 R87 K88 K93 F244 E247 F250 F251 S254 R255 R259 D260 H279 N281 R324
Binding residue
(residue number reindexed from 1)
P23 G26 P27 R63 K64 K69 F217 E220 F223 F224 S227 R228 R232 D233 H252 N254 R297
Enzymatic activity
Enzyme Commision number 3.1.31.1: micrococcal nuclease.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0004518 nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:4qmg, PDBe:4qmg, PDBj:4qmg
PDBsum4qmg
PubMed25242325
UniProtQ7KZF4|SND1_HUMAN Staphylococcal nuclease domain-containing protein 1 (Gene Name=SND1)

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