Structure of PDB 4qbr Chain C Binding Site BS02
Receptor Information
>4qbr Chain C (length=136) Species:
9606
(Homo sapiens) [
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SRERLVYEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLEC
AYQYDDDGYQSYCTICCGGREVLMCDNNNCCRCFCVECVDLLVGPGAAQA
AIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFA
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
4qbr Chain C Residue 701 [
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Receptor-Ligand Complex Structure
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PDB
4qbr
Engineering of a histone-recognition domain in a de novo DNA methyltransferase alters the epigenetic landscape of ESCs
Resolution
1.902 Å
Binding residue
(original residue number in PDB)
C549 C554 C583 C586
Binding residue
(residue number reindexed from 1)
C75 C80 C109 C112
Annotation score
1
Enzymatic activity
Enzyme Commision number
2.1.1.-
2.1.1.37
: DNA (cytosine-5-)-methyltransferase.
External links
PDB
RCSB:4qbr
,
PDBe:4qbr
,
PDBj:4qbr
PDBsum
4qbr
PubMed
UniProt
Q9Y6K1
|DNM3A_HUMAN DNA (cytosine-5)-methyltransferase 3A (Gene Name=DNMT3A)
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