Structure of PDB 4oog Chain C Binding Site BS02

Receptor Information
>4oog Chain C (length=261) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KWPPKLPEIQDLAIRARVFIHKSTIKDKVYLSGSEMINAHNERLEFLGDS
ILNSVMTLIIYNKFPDYSEGQLSTLRMNLVSNEQIKQWSIMYNFHEKLKT
NFDLKDENSNFQNGKLKLYADVFEAYIGGLMEDDPRNNLPKIRKWLRKLA
KPVIEEATRNQVALEKTDKLDMNAKRQLYSLIGYASLRLHYVTVKKPTAV
DPNSIVECRVGDGTVLGTGVGRNIKIAGIRAAENALRDKKMLDFYAKQRA
AIPRSESVLKD
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4oog Chain C Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4oog Structure of a Eukaryotic RNase III Postcleavage Complex Reveals a Double-Ruler Mechanism for Substrate Selection.
Resolution2.5 Å
Binding residue
(original residue number in PDB)
D245 E320
Binding residue
(residue number reindexed from 1)
D49 E124
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.26.3: ribonuclease III.
Gene Ontology
Molecular Function
GO:0003725 double-stranded RNA binding
GO:0004525 ribonuclease III activity
Biological Process
GO:0006364 rRNA processing
GO:0006396 RNA processing

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Molecular Function

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Biological Process
External links
PDB RCSB:4oog, PDBe:4oog, PDBj:4oog
PDBsum4oog
PubMed24703949
UniProtQ02555|RNT1_YEAST Ribonuclease 3 (Gene Name=RNT1)

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