Structure of PDB 4ghl Chain C Binding Site BS02

Receptor Information
>4ghl Chain C (length=122) Species: 33728 (Lake Victoria marburgvirus - Popp) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LSAKDLALLLFTHLPGNNTPFHILAQVLSKIAYKSGKSGAFLDAFHQILS
EGENAQAALTRLSRTFDAFMGVVPPVIRVKNFQTVPRPCQKSLRAVPPNP
TIDKGWVCVYSSEQGETRALKI
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain4ghl Chain C Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4ghl Structural basis for Marburg virus VP35-mediated immune evasion mechanisms.
Resolution2.02 Å
Binding residue
(original residue number in PDB)		L221 G223 H229
Binding residue
(residue number reindexed from 1)		L14 G16 H22
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:4ghl, PDBe:4ghl, PDBj:4ghl
PDBsum4ghl
PubMed23185024
UniProtQ03039|VP35_MABVP Polymerase cofactor VP35 (Gene Name=VP35)

[Back to BioLiP]