Structure of PDB 4c2t Chain C Binding Site BS02

Receptor Information
>4c2t Chain C (length=651) Species: 1299 (Deinococcus radiodurans) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TSSAGPDLLQALNPTQAQAADHFTGPALVIAGAGSGKTRTLIYRIAHLIG
HYGVHPGEILAVTFTNKAAAEMRERAGHLVPGAGDLWMSTFHSAGVRILR
TYGEHIGLRRGFVIYDDDDQLDIIKEVMGSIPGIGAETQPRVIRGIIDRA
KSNLWTPDDLDRSREPFISGLPRDAAAEAYRRYEVRKKGQNAIDFGDLIT
ETVRLFKEVPGVLDKVQNKAKFIHVDEYQDTNRAQYELTRLLASRDRNLL
VVGDPDQSIYKFRGADIQNILDFQKDYPDAKVYMLEHNYRSSARVLEAAN
KLIENNTERLDKTLKPVKEAGQPVTFHRATDHRAEGDYVADWLTRLHGEG
RAWSEMAILYRTNAQSRVIEESLRRVQIPRIVGGVGFYDRREIRDILAYA
RLALNPADDVALRRIIGRPRRGIGDTALQKLMEWARTHHTSVLTACANAA
EQNILDRGAHKATEFAGLMEAMSEAADNYEPAAFLRFVMETSGYLDLLRQ
EEGQVRLENLEELVSAAEEWSQDEANSIADFLDDAALLSSVDDMRTKAEP
EDAVTLMTLHNAKGLEFPVVFIVGVEQGLLPSKGAIAEGPSGIEEERRLF
YVGITRAMERLLMTAAQNRMQFGKTNAAEDSAFLEDIEGLFDTVDPYGQP
I
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4c2t Structural and Mechanistic Insight Into DNA Unwinding by Deinococcus Radiodurans Uvrd.
Resolution3.997 Å
Binding residue
(original residue number in PDB)		F633 G634
Binding residue
(residue number reindexed from 1)		F622 G623
Binding affinityPDBbind-CN: Kd=0.36uM
Enzymatic activity
Catalytic site (original residue number in PDB) K38 T39 D227 E228 Q258 R617
Catalytic site (residue number reindexed from 1) K37 T38 D226 E227 Q257 R606
Enzyme Commision number 5.6.2.4: DNA 3'-5' helicase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0016787 hydrolase activity
GO:0016853 isomerase activity
GO:0016887 ATP hydrolysis activity
GO:0043138 3'-5' DNA helicase activity
GO:0046872 metal ion binding
Biological Process
GO:0000725 recombinational repair
GO:0032508 DNA duplex unwinding
Cellular Component
GO:0005829 cytosol
GO:0033202 DNA helicase complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4c2t, PDBe:4c2t, PDBj:4c2t
PDBsum4c2t
PubMed24143224
UniProtQ9RTI9

[Back to BioLiP]