Structure of PDB 4b27 Chain C Binding Site BS02

Receptor Information
>4b27 Chain C (length=64) Species: 1423 (Bacillus subtilis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDFVVIKAVEDGVNVIGLTRGTDTKFHHSEKLDKGEVIIAQFTEHTSAIK
VRGEALIQTAYGEM
Ligand information
Ligand IDTRP
InChIInChI=1S/C11H12N2O2/c12-9(11(14)15)5-7-6-13-10-4-2-1-3-8(7)10/h1-4,6,9,13H,5,12H2,(H,14,15)/t9-/m0/s1
InChIKeyQIVBCDIJIAJPQS-VIFPVBQESA-N
SMILES
SoftwareSMILES
ACDLabs 10.04O=C(O)C(N)Cc2c1ccccc1nc2
OpenEye OEToolkits 1.5.0c1ccc2c(c1)c(c[nH]2)C[C@@H](C(=O)O)N
OpenEye OEToolkits 1.5.0c1ccc2c(c1)c(c[nH]2)CC(C(=O)O)N
CACTVS 3.341N[CH](Cc1c[nH]c2ccccc12)C(O)=O
CACTVS 3.341N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O
FormulaC11 H12 N2 O2
NameTRYPTOPHAN
ChEMBLCHEMBL54976
DrugBankDB00150
ZINCZINC000000083315
PDB chain4b27 Chain D Residue 81 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB4b27 Trp RNA-Binding Attenuation Protein: Modifying Symmetry and Stability of a Circular Oligomer.
Resolution2.72 Å
Binding residue
(original residue number in PDB)		T25 R26 G27 D29 T30 S53
Binding residue
(residue number reindexed from 1)		T19 R20 G21 D23 T24 S47
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006353 DNA-templated transcription termination
GO:0006355 regulation of DNA-templated transcription
GO:0045947 negative regulation of translational initiation
GO:0060566 positive regulation of termination of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:4b27, PDBe:4b27, PDBj:4b27
PDBsum4b27
PubMed22970197
UniProtP19466|MTRB_BACSU Transcription attenuation protein MtrB (Gene Name=mtrB)

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