Structure of PDB 4atb Chain C Binding Site BS02

Receptor Information

>4atb Chain C (length=332) Species: 10090 (Mus musculus)

SHIPFDFYLCEMAFPRVKPAPDETSFSEALLKRNQDLAPNSAEQASILSL
VTKINNVIDNLIVAPGTVQIEEVRQVGSYKKGTMTTGHNVADLVVILKIL
PTLEAVAALGNKVVESLRAQDPSEVLTMLTNETGFEISSSDATVKILITT
VPPNLRKLDPELHLDIKVLQSALAAIRHARWFEENASQSTVKVLIRLLKD
LRIRFPGFEPLTPWILDLLGHYAVMNNPTRQPLALNVAYRRCLQILAAGL
FLPGSVGITDPCESGNFRVHTVMTLEQQDMVCYTAQTLVRILSHGGFRKI
LGQEGDASYLASEISTWDGVIVTPSEKAYEKP

Ligand information

• Ligand ID: MG
• InChI: InChI=1S/Mg/q+2
• InChIKey: JLVVSXFLKOJNIY-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mg+2]
  CACTVS 3.341: [Mg++]
• Formula: Mg
• Name: MAGNESIUM ION
• DrugBank: DB01378
• PDB chain: 4atb Chain C Residue 1363

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4atb NF45 Dimerizes with NF90, Zfr and Spnr Via a Conserved Domain that Has a Nucleotidyltransferase Fold.
• Resolution: 3.1 Å
• Binding residue (original residue number in PDB): S107 D121
• Binding residue (residue number reindexed from 1): S78 D92
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0003677 DNA binding
• GO:0003725 double-stranded RNA binding

Biological Process

• GO:0045893 positive regulation of DNA-templated transcription

Cellular Component

• GO:0005634 nucleus
• GO:0005654 nucleoplasm
• GO:0005730 nucleolus
• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4atb, PDBe:4atb, PDBj:4atb
• PDBsum: 4atb
• PubMed: 22833610
• UniProt: Q9CXY6|ILF2_MOUSE Interleukin enhancer-binding factor 2 (Gene Name=Ilf2)