Structure of PDB 3zk4 Chain C Binding Site BS02

Receptor Information

>3zk4 Chain C (length=568) Species: 3873 (Lupinus luteus)

AYIKATPNVLGFEGHYTEWVTLQYSNNKPSIDDWIGVFSPANFSASTCPG
ENKMTNPPFLCSAPIKFQYANFSSHSYKDTGKGSLKLQLINQRSDFSFAL
FTGGLTNPKLIAVSNKVSFVNPNAPVYPRLAQGKTWDEITVTWTSGYDIN
DAEPFVEWGPKEGNLVKTPAGTLTFDRNTMCGAPARTVGWRDPGYIHTSF
LKELWPNREYTYKLGHRLFNGTTIWSKEYHFKASPYPGQSSVQRVVIFGD
MGKAEADGSNEYNNFQPGSLNTTKQIIQDLEDIDIVFHIGDLCYANGYIS
QWDQFTAQIEPIASTVPYMTASGNHERDWPGTGSFYGNLDSGGECGVPAQ
TMFFVPAENREKFWYSTDYGMFRFCIAHTELDWRKGTEQYEFIEKCLASV
DRQKQPWLIFLAHRVLGYSSAGFYVQEGSFEEPMGREDLQHLWQKYKVDI
AMYGHVHNYERTCPIYQNVCTNKEKHNYKGNLNGTIHVVVGGGGASLAEF
APINTTWSIFKDHDFGFVKLTAFDHSNLLLEYRKSSDGQVYDSFTISRDY
RDILACSVDSCPTTTLAS

Ligand information

• Ligand ID: MN
• InChI: InChI=1S/Mn/q+2
• InChIKey: WAEMQWOKJMHJLA-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Mn+2]
  CACTVS 3.341: [Mn++]
• Formula: Mn
• Name: MANGANESE (II) ION
• DrugBank: DB06757
• PDB chain: 3zk4 Chain C Residue 801

Receptor-Ligand Complex Structure

Structure summary

• PDB: 3zk4 The Structure of a Purple Acid Phosphatase Involved in Plant Growth and Pathogen Defence Exhibits a Novel Immunoglobulin-Like Fold
• Resolution: 1.65 Å
• Binding residue (original residue number in PDB): D313 N346 H435 H477
• Binding residue (residue number reindexed from 1): D291 N324 H413 H455
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): D272 D313 Y316 N346 H347 H435 F445 Y446 H477 H479
• Catalytic site (residue number reindexed from 1): D250 D291 Y294 N324 H325 H413 F423 Y424 H455 H457
• Enzyme Commision number: 3.1.3.2: acid phosphatase.

Gene Ontology

Molecular Function

• GO:0003993 acid phosphatase activity
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:3zk4, PDBe:3zk4, PDBj:3zk4
• PDBsum: 3zk4
• PubMed: 25075326
• UniProt: Q8VX11