Structure of PDB 3slp Chain C Binding Site BS02
Receptor Information
>3slp Chain C (length=226) Species:
10710
(Lambdavirus lambda) [
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MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKPRSGKKW
PDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNV
TESPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAI
KSAYMAQVQYSMWVTRKNAWYFANYDPRMKREGLHYVVIERDEKYMASFD
EIVPEFIEKMDEALAEIGFVFGEQWR
Ligand information
Ligand ID
CA
InChI
InChI=1S/Ca/q+2
InChIKey
BHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Ca+2]
Formula
Ca
Name
CALCIUM ION
ChEMBL
DrugBank
DB14577
ZINC
PDB chain
3slp Chain C Residue 227 [
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Receptor-Ligand Complex Structure
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PDB
3slp
Crystal structures of {lambda} exonuclease in complex with DNA suggest an electrostatic ratchet mechanism for processivity.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
D119 E129
Binding residue
(residue number reindexed from 1)
D119 E129
Annotation score
4
Enzymatic activity
Catalytic site (original residue number in PDB)
E93 E102 D109 E129 L130 K131
Catalytic site (residue number reindexed from 1)
E93 E102 D109 E129 L130 K131
Enzyme Commision number
3.1.11.3
: exodeoxyribonuclease (lambda-induced).
Gene Ontology
Molecular Function
GO:0004527
exonuclease activity
GO:0046872
metal ion binding
GO:0051908
double-stranded DNA 5'-3' DNA exonuclease activity
Biological Process
GO:0006259
DNA metabolic process
View graph for
Molecular Function
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Biological Process
External links
PDB
RCSB:3slp
,
PDBe:3slp
,
PDBj:3slp
PDBsum
3slp
PubMed
21730170
UniProt
P03697
|EXO_LAMBD Exonuclease (Gene Name=exo)
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