Structure of PDB 3o37 Chain C Binding Site BS02
Receptor Information
>3o37 Chain C (length=176) Species:
9606
(Homo sapiens) [
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PNEDWCAVCQNGGELLCCEKCPKVFHLSCHVPTLTNFPSGEWICTFCRDL
SKPEVEYDCEKKKTEGLVKLTPIDKRKCERLLLFLYCHEMSLAFQDPVPL
TVPDYYKIIKNPMDLSTIKKRLQEDYSMYSKPEDFVADFRLIFQNCAEFN
EPDSEVANAGIKLENYFEELLKNLYP
Ligand information
>3o37 Chain H (length=10) Species:
9606
(Homo sapiens) [
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ARTKQTARKS
Receptor-Ligand Complex Structure
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PDB
3o37
TRIM24 links a non-canonical histone signature to breast cancer.
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
D934 E978
Binding residue
(residue number reindexed from 1)
D104 E148
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:3o37
,
PDBe:3o37
,
PDBj:3o37
PDBsum
3o37
PubMed
21164480
UniProt
O15164
|TIF1A_HUMAN Transcription intermediary factor 1-alpha (Gene Name=TRIM24)
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