Structure of PDB 3f9z Chain C Binding Site BS02

Receptor Information
>3f9z Chain C (length=160) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFV
VEFHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNR
LGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKA
SIEAHPWLKH
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB3f9z Structural origins for the product specificity of SET domain protein methyltransferases.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		L222 S267
Binding residue
(residue number reindexed from 1)		L30 S75
Enzymatic activity
Enzyme Commision number 2.1.1.-
2.1.1.361: [histone H4]-lysine(20) N-methyltransferase.
Gene Ontology
Molecular Function
GO:0042799 histone H4K20 methyltransferase activity

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Molecular Function
External links
PDB RCSB:3f9z, PDBe:3f9z, PDBj:3f9z
PDBsum3f9z
PubMed19088188
UniProtQ9NQR1|KMT5A_HUMAN N-lysine methyltransferase KMT5A (Gene Name=KMT5A)

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