Structure of PDB 3e3j Chain C Binding Site BS02

Receptor Information
>3e3j Chain C (length=833) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNDFSDIELAAIPFNTLADHYGERLAREQLALEHESYEMGEARFRKMFLI
TTLLPKMIARINDWFEEVKAKRGKRPTAFQFLQEIKPEAVAYITIKTTLA
CLTSADNTTVQAVASAIGRAIEDEARFGRIRDLEAKHFKKNVKAFMQVVE
ADMLSKGLLGGEAWSSWHKEDSIHVGVRCIEMLIESTGMVSLHRQNAGVV
GQDSETIELAPEYAEAIAGISLMFQPCVVPPKPWTGITGGGYWANGRRPL
ALVRTHSKKALMRYEDVYMPEVYKAINIAQNTAWKINKKVLAVANVITKW
KHCPVEDIPAIEREELPMKPEDIDMNPEALTAWKRAAAAVYRKDKARKSR
RISLEFMLEQANKFANHKAIWFPYNMDWRGRVYAVSMFNPQGNDMTKGLL
TLAKGKPIGKEGYYWLKIHGANCAGVDKVPFPERIKFIEENHENIMACAK
SPLENTWWAEQDSPFCFLAFCFEYAGVQHHGLSYNCSLPLAFDGSCSGIQ
HFSAMLRDEVGGRAVNLLPSETVQDIYGIVAKKVNEILQADAINGTDNEV
VTVTISEKVKLGTKALAGQWLAYGVTRSVTKRSVMTLAYGSKEFGFRQQV
LEDTIQPAIDSGKGLMFTQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLK
SAAKLLAAEVKDKKTGEILRKRCAVHWVTPDGFPVWQEYKKPIQTRLNLM
FLGQFRLQPTINTNKDSEIDAHKQESGIAPNFVHSQDGSHLRKTVVWAHE
KYGIESFALIHDSFGTIPADAANLFKAVRETMVDTYESCDVLADFYDQFA
DQLHESQLDKMPALPAKGNLNLRDILESDFAFA
Ligand information
Receptor-Ligand Complex Structure
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PDB3e3j The structure of a transcribing t7 RNA polymerase in transition from initiation to elongation
Resolution6.7 Å
Binding residue
(original residue number in PDB)		K95 R96 G97 K98 P100 H211 G235 F644 R647 K704 L747 N748
Binding residue
(residue number reindexed from 1)		K71 R72 G73 K74 P76 H174 G198 F594 R597 K654 L697 N698
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0019083 viral transcription
GO:0039695 DNA-templated viral transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:3e3j, PDBe:3e3j, PDBj:3e3j
PDBsum3e3j
PubMed18948533
UniProtP00573|RPOL_BPT7 T7 RNA polymerase (Gene Name=1)

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