Structure of PDB 3a4k Chain C Binding Site BS02

Receptor Information
>3a4k Chain C (length=297) Species: 71421 (Haemophilus influenzae Rd KW20) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KSALEKLLSLIENLTNQEFKQATNSLISFIYKLNRNEVIELVRSIGILPE
AIKPSSTQEKLFSKAGDIVLAKAFQLLNLNSKPLEQGNAGDVIALSKEFN
YGLVADAKSFRLSRTAKNQKDFKVKALSEWREDKDYAVLTAPFFQYPTTK
SQIFKQSLDENVLLFSWEHLAILLQLDLEETNIFSFEQLWNFPKKQSKKT
SVSDAENNFMRDFNKYFMDLFKIDKDTLNQLLQKEINFIEERSLIEKEYW
KKQINIIKNFTREEAIEALLKDINMSSKIETIDSFIKGIKSNDRLYL
Ligand information
Receptor-Ligand Complex Structure
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PDB3a4k Structures of restriction endonuclease HindIII in complex with its cognate DNA and divalent cations
Resolution2.17 Å
Binding residue
(original residue number in PDB)		L49 E60 S64 K110 S111 F112 R113 R116 T117 A118 N120 D123 K125
Binding residue
(residue number reindexed from 1)		L48 E59 S63 K108 S109 F110 R111 R114 T115 A116 N118 D121 K123
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:3a4k, PDBe:3a4k, PDBj:3a4k
PDBsum3a4k
PubMed19966419
UniProtP43870|T2D3_HAEIN Type II restriction enzyme HindIII (Gene Name=hindIIIR)

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