Structure of PDB 2vt4 Chain C Binding Site BS02

Receptor Information
>2vt4 Chain C (length=263) Species: 9103 (Meleagris gallopavo) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QWEAGMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADL
VVGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAID
RYLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQ
ALKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVALRVYREAKEQI
REHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNRDLVPDWLFVAFNWLGY
ANSAMNPIIYCRS
Ligand information
Ligand IDNA
InChIInChI=1S/Na/q+1
InChIKeyFKNQFGJONOIPTF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[Na+]
FormulaNa
NameSODIUM ION
ChEMBL
DrugBankDB14516
ZINC
PDB chain2vt4 Chain C Residue 401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2vt4 Structure of a Beta1-Adrenergic G-Protein-Coupled Receptor.
Resolution2.7 Å
Binding residue
(original residue number in PDB)
C192 Y193 D195 P196 C198
Binding residue
(residue number reindexed from 1)
C154 Y155 D157 P158 C160
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004935 adrenergic receptor activity
Biological Process
GO:0007186 G protein-coupled receptor signaling pathway
Cellular Component
GO:0016020 membrane

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:2vt4, PDBe:2vt4, PDBj:2vt4
PDBsum2vt4
PubMed18594507
UniProtP07700|ADRB1_MELGA Beta-1 adrenergic receptor (Gene Name=ADRB1)

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