Structure of PDB 2uzp Chain C Binding Site BS02

Receptor Information

>2uzp Chain C (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SMHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLI
PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTS
RNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADA

Ligand information

InChI=1S/Co/q+2

XLJKHNWPARRRJB-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Co+2]
CACTVS 3.341	[Co++]

Formula

Co

Name

COBALT (II) ION

PDB chain

2uzp Chain C Residue 1295 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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PDB	2uzp Crystal Structure of C2 Domain of Protein Kinase C Gamma
Resolution	2.0 Å
Binding residue (original residue number in PDB)	S-1 M0 H154
Binding residue (residue number reindexed from 1)	S1 M2 H3
Annotation score	1

Enzymatic activity

Enzyme Commision number

2.7.11.13: protein kinase C.

External links

PDB	RCSB:2uzp, PDBe:2uzp, PDBj:2uzp
PDBsum	2uzp
PubMed
UniProt	P05129\|KPCG_HUMAN Protein kinase C gamma type (Gene Name=PRKCG)

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