Structure of PDB 2hnv Chain C Binding Site BS02
Receptor Information
>2hnv Chain C (length=81) Species:
9913
(Bos taurus) [
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VRTCLPCGPGGKGRCFGPSICCGDELGCFVGTAEALRCQEENYLPSPCQS
GVKPCGSGGRCAAAGICCSPDGCHEDPACDP
Ligand information
Ligand ID
TYR
InChI
InChI=1S/C9H11NO3/c10-8(9(12)13)5-6-1-3-7(11)4-2-6/h1-4,8,11H,5,10H2,(H,12,13)/t8-/m0/s1
InChIKey
OUYCCCASQSFEME-QMMMGPOBSA-N
SMILES
Software
SMILES
ACDLabs 10.04
O=C(O)C(N)Cc1ccc(O)cc1
OpenEye OEToolkits 1.5.0
c1cc(ccc1C[C@@H](C(=O)O)N)O
OpenEye OEToolkits 1.5.0
c1cc(ccc1CC(C(=O)O)N)O
CACTVS 3.341
N[CH](Cc1ccc(O)cc1)C(O)=O
CACTVS 3.341
N[C@@H](Cc1ccc(O)cc1)C(O)=O
Formula
C9 H11 N O3
Name
TYROSINE
ChEMBL
CHEMBL925
DrugBank
DB00135
ZINC
ZINC000000266964
PDB chain
2hnv Chain C Residue 2 [
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Receptor-Ligand Complex Structure
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PDB
2hnv
Contributions of the interdomain loop, amino terminus, and subunit interface to the ligand-facilitated dimerization of neurophysin: crystal structures and mutation studies of bovine neurophysin-I.
Resolution
2.5 Å
Binding residue
(original residue number in PDB)
C10 C21 F22 G23 P24 C44 E47 C54
Binding residue
(residue number reindexed from 1)
C4 C15 F16 G17 P18 C38 E41 C48
Annotation score
4
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0005185
neurohypophyseal hormone activity
Cellular Component
GO:0005576
extracellular region
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Molecular Function
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Cellular Component
External links
PDB
RCSB:2hnv
,
PDBe:2hnv
,
PDBj:2hnv
PDBsum
2hnv
PubMed
17192588
UniProt
P01175
|NEU1_BOVIN Oxytocin-neurophysin 1 (Gene Name=OXT)
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