Structure of PDB 2f4l Chain C Binding Site BS02

Receptor Information
>2f4l Chain C (length=278) Species: 243274 (Thermotoga maritima MSB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
HMKVVPAQRCVYSFSANMAPVEEVYPGEQVVFETLDALGGSSKVNPATGP
VFVNGVKPGDTLKVRIKRIELPRRGMIVTGKGFGVLGDEVEGFHTKELEI
EKWAVLFDGVRIPIHPMVGVIGVAPQEGEYPTGTAHRHGGNMDTKEITEN
VTVHLPVFQEGALLALGDVHATMGDGEVCVSACEVPAKVVVEIDVSKEEI
KWPVVETNDAYYIIVSLPDIEEALKEVTRETVWFIQRRKTIPFTDAYMLA
SLSVDVGISQLVNPAKTAKARIPKYIFT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2f4l Chain C Residue 3401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2f4l Crystal structure of Acetamidase, putative (tm0119) from THERMOTOGA MARITIMA at 2.50 A resolution
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D173 H175 E189
Binding residue
(residue number reindexed from 1)		D168 H170 E184
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:2f4l, PDBe:2f4l, PDBj:2f4l
PDBsum2f4l
PubMed
UniProtQ9WXX3

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