Structure of PDB 2e6b Chain C Binding Site BS02

Receptor Information
>2e6b Chain C (length=232) Species: 300852 (Thermus thermophilus HB8) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MRILVTNDDGIYSPGLWALAEAASQFGEVFVAAPDTHAITIAHPVRAYPH
PSPLHAPHFPAYRVRGTPADCVALGLHLFGPVDLVLSGVNLGSNLGHEIW
HSGTVAAAKQGYLFGLSAAAFSVPLNGEVPDFAGLRPWLLRTLETLLRLE
RPFLVNVNLPLRPKGFLWTRQSVRAYEGVVIPGEDPMGRPFYWFAPRPLK
EAEEGTDRWAVAQGFVSATPLRLDLTDETRLQ
Ligand information
Ligand IDWO4
InChIInChI=1S/4O.W/q;;2*-1;
InChIKeyPBYZMCDFOULPGH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0[O-][W](=O)(=O)[O-]
ACDLabs 10.04
CACTVS 3.341		[O-][W]([O-])(=O)=O
FormulaO4 W
NameTUNGSTATE(VI)ION
ChEMBL
DrugBank
ZINC
PDB chain2e6b Chain C Residue 2302 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2e6b Crystal Structure of the Stationary Phase Survival Protein SurE with Metal Ion and AMP
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D8 N96 S108 G109 T110
Binding residue
(residue number reindexed from 1)		D8 N90 S102 G103 T104
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.5: 5'-nucleotidase.
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0004309 exopolyphosphatase activity
GO:0008252 nucleotidase activity
GO:0008253 5'-nucleotidase activity
GO:0008254 3'-nucleotidase activity
GO:0016787 hydrolase activity
GO:0046872 metal ion binding
GO:0106411 XMP 5'-nucleosidase activity
Cellular Component
GO:0005737 cytoplasm

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:2e6b, PDBe:2e6b, PDBj:2e6b
PDBsum2e6b
PubMed17561111
UniProtQ53W92|SURE_THET8 5'-nucleotidase SurE (Gene Name=surE)

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