Structure of PDB 2d6f Chain C Binding Site BS02

Receptor Information
>2d6f Chain C (length=485) Species: 145262 (Methanothermobacter thermautotrophicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDWEKVGLKMGLEIHQQLDTESKLFCPCRTELTDSEPDHDIVRNLRPTAF
EEAMRKLHFHYENYHEETCLVEADEEPPHPLNPEALEIAVTIALLLNMRV
VDEFHTMRKQVIDGSNTGGFQRTGLVATDGHLETPQGTVKIENLCLEEDA
ARRIRETGDGVVFRLDRLGIPLVEITTDPSMSDPQQLREVAYQIGQILRS
TRVKRGLGTIRQDLNISIRDGARVEVKGVQDLDLIPEIVEREVKRQLSLV
EIRDTLQERGAVVEDKIFDVSEVFADTESRIISSAESVLAVKLRGFDGLI
GVEIQPGRRLGTEMADYAKKRGVSGIFHTDELPAYGITEEEVRGLRDAVG
ASQGDAVVMVAHERVTAENALREVIRRAEMAIQGVPEETRKALPDGNTQY
LRPLPTSSRMYLETDIPLFRIEDDLLEGIRRNLPELPSEKKERIMRDYGL
SEDLASQLVKRNLVDEFDTTVIASLLAYTLRELRR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2d6f Chain C Residue 900 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2d6f Structural basis of RNA-dependent recruitment of glutamine to the genetic code
Resolution3.15 Å
Binding residue
(original residue number in PDB)		C28 C79 E82
Binding residue
(residue number reindexed from 1)		C28 C69 E72
Annotation score1
Enzymatic activity
Enzyme Commision number 6.3.5.-
Gene Ontology
Molecular Function
GO:0003824 catalytic activity
GO:0004812 aminoacyl-tRNA ligase activity
GO:0005524 ATP binding
GO:0016874 ligase activity
GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor
GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
Biological Process
GO:0006412 translation
GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2d6f, PDBe:2d6f, PDBj:2d6f
PDBsum2d6f
PubMed16809540
UniProtO26803|GATE_METTH Glutamyl-tRNA(Gln) amidotransferase subunit E (Gene Name=gatE)

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