Structure of PDB 2cjs Chain C Binding Site BS02

Receptor Information
>2cjs Chain C (length=54) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APTCGICHKTKFADGCGHNCSYCQTKFCARCGGRVSLRSNKVMWVCNLCR
KQQE
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2cjs Chain C Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2cjs Structural Basis for a Munc13-1 Homodimer to Munc13-1/Rim Heterodimer Switch.
Resolution1.78 Å
Binding residue
(original residue number in PDB)		C108 C111 C134 C137
Binding residue
(residue number reindexed from 1)		C20 C23 C46 C49
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0031267 small GTPase binding
Biological Process
GO:0006887 exocytosis
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:2cjs, PDBe:2cjs, PDBj:2cjs
PDBsum2cjs
PubMed16732694
UniProtQ9JIS1|RIMS2_RAT Regulating synaptic membrane exocytosis protein 2 (Gene Name=Rims2)

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