Structure of PDB 1ytz Chain C Binding Site BS02

Receptor Information
>1ytz Chain C (length=159) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDQQAEARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNP
TKEELDAIIEEVDEDGSGTIDFEEFLVMMVRQMKEDAKGKSEEELANCFR
IFDKNADGFIDIEELGEILRATGEHVTEEDIEDLMKDSDKNNDGRIDFDE
FLKMMEGVQ
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1ytz Chain C Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ytz Ca2+-regulated structural changes in troponin
Resolution3.0 Å
Binding residue
(original residue number in PDB)		D141 N143 D145 R147 I148 E152
Binding residue
(residue number reindexed from 1)		D139 N141 D143 R145 I146 E150
Annotation score4
Enzymatic activity
Catalytic site (original residue number in PDB) V44
Catalytic site (residue number reindexed from 1) V42
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0046872 metal ion binding
Biological Process
GO:0003009 skeletal muscle contraction
Cellular Component
GO:0005861 troponin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ytz, PDBe:1ytz, PDBj:1ytz
PDBsum1ytz
PubMed15784741
UniProtP02588|TNNC2_CHICK Troponin C, skeletal muscle (Gene Name=TNNC2)

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