Structure of PDB 1tx3 Chain C Binding Site BS02

Receptor Information
>1tx3 Chain C (length=255) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSD
LTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSI
ENLFEEKQNDTADILLVKQFYELLDVKTRNISKSAQAPNIISAYKLAQTC
AKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINW
AAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKP
FKKYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1tx3 Ca2+ binding in the active site of HincII: implications for the catalytic mechanism
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H31 Q109 N110 T130 R131 N132 K135 S136 A137 Q138 P140 N141 S144 Y146 K147 A205 M206 Q207
Binding residue
(residue number reindexed from 1)		H30 Q108 N109 T128 R129 N130 K133 S134 A135 Q136 P138 N139 S142 Y144 K145 A203 M204 Q205
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1tx3, PDBe:1tx3, PDBj:1tx3
PDBsum1tx3
PubMed15491133
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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