Structure of PDB 1mhe Chain C Binding Site BS02
Receptor Information
>1mhe Chain C (length=273) Species:
9606
(Homo sapiens) [
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SHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDRRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPVTLRW
Ligand information
>1mhe Chain Q (length=9) [
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VMAPRTVLL
Receptor-Ligand Complex Structure
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PDB
1mhe
Structural features impose tight peptide binding specificity in the nonclassical MHC molecule HLA-E.
Resolution
2.85 Å
Binding residue
(original residue number in PDB)
Y7 M45 E63 I73 F74 N77 W97 K146 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y6 M44 E62 I72 F73 N76 W96 K145 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1mhe
,
PDBe:1mhe
,
PDBj:1mhe
PDBsum
1mhe
PubMed
9660937
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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