Structure of PDB 1mfr Chain C Binding Site BS02

Receptor Information

>1mfr Chain C (length=171) Species: 8400 (Aquarana catesbeiana) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

VSQVRQNYHSDCEAAVNRMLNLELYASYTYSSMYAFFDRDDVALHNVAEF
FKEHSHEEREHAEKFMKYQNKRGGRVVLQDIKKPERDEWGNTLEAMQAAL
QLEKTVNQALLDLHKLATDKVDPHLCDFLESEYLEEQVKDIKRIGDFITN
LKRLGLPENGMGEYLFDKHSV

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

1mfr Chain C Residue 177 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1mfr Crystal structure of bullfrog M ferritin at 2.8 A resolution: analysis of subunit interactions and the binuclear metal center
Resolution	2.8 Å
Binding residue (original residue number in PDB)	E58 E103 Q137 D140
Binding residue (residue number reindexed from 1)	E58 E103 Q137 D140
Annotation score	1

Enzymatic activity

Enzyme Commision number

1.16.3.1: ferroxidase.

Gene Ontology

	Molecular Function
GO:0004322	ferroxidase activity
GO:0008198	ferrous iron binding
GO:0008199	ferric iron binding
GO:0016491	oxidoreductase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion

	Cellular Component
GO:0005737	cytoplasm

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External links

PDB	RCSB:1mfr, PDBe:1mfr, PDBj:1mfr
PDBsum	1mfr
PubMed	10439069
UniProt	P07798\|FRI2_AQUCT Ferritin, middle subunit

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