Structure of PDB 1h38 Chain C Binding Site BS02

Receptor Information
>1h38 Chain C (length=857) Species: 10760 (Escherichia phage T7) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NTINIAKNDFSDIELAAIPFNTLADHYGERLAREQLALEHESYEMGEARF
RKMFERQLKAGEVADNAAAKPLITTLLPKMIARINDWFEEVKAKRGKRPT
AFQFLQEIKPEAVAYITIKTTLACLTSADNTTVQAVASAIGRAIEDEARF
GRIRDLEAKHFKKNVEEQLNKRVGHVYKKAFMQVVEADMLSKGLLGGEAW
SSWHKEDSIHVGVRCIEMLIESTGMVSLHRQNAGVVGQDSETIELAPEYA
EAIATRAGALAGISPMFQPCVVPPKPWTGITGGGYWANGRRPLALVRTHS
KKALMRYEDVYMPEVYKAINIAQNTAWKINKKVLAVANVITKWKHCPVED
IPAIEALTAWKRAAAAVYRKDKARKSRRISLEFMLEQANKFANHKAIWFP
YNMDWRGRVYAVSMFNPQGNDMTKGLLTLAKGKPIGKEGYYWLKIHGANC
AGVDKVPFPERIKFIEENHENIMACAKSPLENTWWAEQDSPFCFLAFCFE
YAGVQHHGLSYNCSLPLAFDGSCSGIQHFSAMLRDEVGGRAVNLLPSETV
QDIYGIVAKKVNEILQADAINGTDNEVVTVTDENTGEISEKVKLGTKALA
GQWLAYGVTRSVTKRSVMTLAYGSKEFGFRQQVLEDTIQPAIDSGKGLMF
TQPNQAAGYMAKLIWESVSVTVVAAVEAMNWLKSAAKLLAAEVKDKKTGE
ILRKRCAVHWVTPDGFPVWQEYKKPIQTRLNLMFLGQFRDSEIDAHKQES
GIAPNFVHSQDGSHLRKTVVWAHEKYGIESFALIHDSFGTIPADAANLFK
AVRETMVDTYESCDVLADFYDQFADQLHESQLDKMPALPAKGNLNLRDIL
ESDFAFA
Ligand information
Receptor-Ligand Complex Structure
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PDB1h38 Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution
Resolution2.9 Å
Binding residue
(original residue number in PDB)		N171 K172 R386 K389 A390 S393 R394 R425 Q435 G436 Y639 I810 D812
Binding residue
(residue number reindexed from 1)		N170 K171 R369 K372 A373 S376 R377 R408 Q418 G419 Y622 I784 D786
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0019083 viral transcription
GO:0039695 DNA-templated viral transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1h38, PDBe:1h38, PDBj:1h38
PDBsum1h38
PubMed12422209
UniProtP00573|RPOL_BPT7 T7 RNA polymerase (Gene Name=1)

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