Structure of PDB 8ova Chain By Binding Site BS02

Receptor Information
>8ova Chain By (length=186) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIKSHDQITFPEDVTVSVKDRIVTVKGKRGTLTKDLRHLQLDFRVNKKL
RTFTAVRWFGNKINNSTINTALSHVRNMITGVTKGFRFKVRFAYAHFPIS
VTVENQLVEIRNFLGEKRVRRQVVADDVKVYRTDAALVKDELVLEGNDLE
QVSREAAVMHQLCLVKKKDIRKFLDGIYVQTKTNIE
Ligand information
>8ova Chain BG (length=183) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gugagauugugaagggaucucgcaggcaucgugagggaaguaugggguag
uacgagaggaacucccaugccgugccucugguuucuggaguuugucgaag
ggcaagugcuccgacgcuaucgcacggugguucucggcugaacgccucua
agccagaaaccagucccaagaccgggugcccgu
<<<<<<<.........>>>>>>>.<<<<<<....<<<<.<<<<<<<<...
............>>>>>>>><<<<<...<<<<....<<<<<<<<<.....
.>>>>..>>>>>...>>>>..>>>>>.<<<<..<.<<<<...........
>>>>.>..>>>>.>>>>.......>>>>>>...
Receptor-Ligand Complex Structure
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PDB8ova A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
Resolution2.47 Å
Binding residue
(original residue number in PDB)		H39 S66 N69 T70 S73 H74 F97 E116 K117 R118 E150 S153 Q161 K172
Binding residue
(residue number reindexed from 1)		H39 S66 N69 T70 S73 H74 F97 E116 K117 R118 E150 S153 Q161 K172
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8ova, PDBe:8ova, PDBj:8ova
PDBsum8ova
PubMed37985661
UniProtQ38CD0

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