Structure of PDB 4v8m Chain By Binding Site BS02

Receptor Information
>4v8m Chain By (length=189) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKIKSHDQITFPEDVTVSVKDRIVTVKGKRGTLTKDLRHLQLDFRVNKKL
RTFTAVRWFGNKINNSTINTALSHVRNMITGVTKGFRFKVRFAYAHFPIS
VTVENQLVEIRNFLGEKRVRRQVVADDVKVYRTDAALVKDELVLEGNDLE
QVSREAAVMHQLCLVKKKDIRKFLDGIYVQTKTNIEVDE
Ligand information
>4v8m Chain BB (length=1465) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ucccaacugcagaccguacucaucaccgcaucagguccccaagcaucgaa
ugcucugguaacauagagaaagguacacucagggaagucggcaaaauaga
ugcguaaguucgcaagaagcauuggcucugagggcaaaguggggguccac
aggagggccaguguccuuugaaggcuacccucccgagccguaucuacuaa
ccuccuucugguguguuguuuuuacgucucacucccgcgcagguguuuuc
gcuuccuuuuuuugguugcgcaccuacaaauugccaacucagaacugcuu
acggcggggaauccaacuguauaauuaaaacauagguuugugaugcaucc
aagugguguaugucgcaaacugauuucugcccagugcucugaaugucaac
gugagagauucaccgacgcgcggguaaacggcgggaguaacuaugacucu
cuuaagguagccaaaugccucgucuuccaauuagagacgcgcaugaaugg
auuaaugagauucccucugucccgaguuacuaucuagcgaaacgacaguc
aagggaacggacuugaagggcuaagcggggaaagaagacccuguugaguu
ugacuccagucuggcucugugcggcgacuuuggagguguaguauaggugg
aagcgcaagcucaaaugaaauaccaccacucggaacguugcuucacuuau
cgaaugaagagaccaaugguuguuuugcgcagucuucgggcugugcgccg
ucuaggcugggcauaauugugguguuucuuucaccgccacgggaggggug
uugguuuuuuauccuccucuccguuucuccuuuucucucuuucucccuuu
uuuugggcguuugaggguuggugacccgugggcgcccacgcgugcggaac
uacugcgccaacggggugggaacuuuucguuucuucuccggagucuuguu
ucgagacaucugccagauggggaguuuggcuggggcggcauaucuguuac
acgacaacgcagguguccuaaggcgagcucagugggaacagaaaucucac
guggaacacaagcguaaaugcuugcuugauuaacgauuuccaguacgaau
cgagacugcgaaagcaaggccagcgauccuuugcgaagaacaggaaauau
gaacaaaucauaccagaggugucagaauaauuaccacagggauaacuggc
uuguggcggccaagcguucauagcgacgucgcuuuuugauccuucgaugu
cggcucuuccuaaccuagcgccgcagaagacgcuaaggguuggauuguuc
acccacugacagggaacgugagcuggguuuagaccgucgugagacagguu
gguuuuacccuacuuggcuggagauugcgaguaaaagauuauccgcgcaa
agcggaggcaguccguuuuuuucugggucugccguucgguggcaugugcu
uggcgcugccaucuc
.........................<<......>>......<<<<<...>
>>>>.........<<<<....<<<..<<<<.<<...............<<
<<<...............>>>>><..<<<<<<<<<<<..<<<<<......
.<<<<<....<<<.<<<....>>>.>>>>>>>>.<<<.<<<<...<.<<<
<.............>>>>.>..>>>>.>>>..>>>>>.....<<<....<
<<..<<.......>>..>>>>>>.......>>>>>..>>>>>>..>....
......<<<<<<<<<..<<<.........>>>..<<<<<<<....<<<..
.....>>>......>>>>>>>...<<..<<<..<<<<<......<<....
<<<<.....>>>>....>>...>>>..>>>>><<<<<<.......>>>>>
>....................<<<<<.......>>>>>...........>
>....>>.>>>>>>>.....>>.>>>>.>>>.>>>>............<<
<<<........>>>>>...<<<<<<..<<<.<<......<<<<.<..<<<
..<<<<..<<<<<<<...<<..<<<<<<<<..<............<<<<<
...<....>.............>>>>>...>..>>.>>>>>>..>>...<
<<<<.....<<<.....<...<<..<<<<<<<<<....>>>>>>>>>..>
.>>..<..<<<<........<<<<.......>>>>.<<<<<<<...<...
...<.......>..>..<<.<<<.<<<<<.....<.<<<...........
....>>>.>...>>>>>.>>>.>>>>>>>>>..>>>>.....>.......
...........<<<<<.<<<<<<.....>>>>>>.>>>>>...>>>...>
>>>>.......>>>>>>>...>>>>...<<.......>>..<<<<<<...
........>>>>>>.......<<<<<<<...<<<<<<.......>>>>>>
.....<<....((>>....>>>>>>>...<<..<<<<<<.......>>>>
>>.>>.<<<....>>>..))........<<<<<..............<<<
<.......>>>>.>>>>>..........>>>....>>>>>.......<<.
<...<<<<<<...<<.......>>...>>>>>>....>.>.>.......<
.<<<.<<<<<<..<<<<<<<.<......>.>>>>>..>>.<<<.......
..>>>.....>>>>>..>...>>>..>....<<<<<<<....>>>.>>>>
....>>..>>>.>>>>>>.......................<<<<<....
.>>>>><<<<<<<<<........>>>>.>>>>>....<<<<<<<.<<<<.
..>>>>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB4v8m High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome.
Resolution5.57 Å
Binding residue
(original residue number in PDB)		K166 K168 D169 I170 R171 K172
Binding residue
(residue number reindexed from 1)		K166 K168 D169 I170 R171 K172
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0042254 ribosome biogenesis
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0022625 cytosolic large ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v8m, PDBe:4v8m, PDBj:4v8m
PDBsum4v8m
PubMed23395961
UniProtQ38CD0

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