Structure of PDB 8ova Chain Bv Binding Site BS02
Receptor Information
>8ova Chain Bv (length=143) Species:
5702
(Trypanosoma brucei brucei) [
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KVSRKSPEYSTVRKSCKPGTIAIILAGRFRGRRAVILKQLPKNGPLVISG
PMKYSGVPIRRIDSRYIIATSTRVDLTGVDTSAITPEIFKRETVSDERAQ
LQNAIDTALIQAIKKDPLGKEMAGYLHSVFTIKPGDAPHRLKW
Ligand information
>8ova Chain BF (length=69) [
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ucgaaucgccacuucucuuauccggugggcugcccgcccggcgcccagua
ccuucauuuucacaagauc
.......<<<.............<<<<<<<.>>>>>>>.>>>........
...................
Receptor-Ligand Complex Structure
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PDB
8ova
A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei.
Resolution
2.47 Å
Binding residue
(original residue number in PDB)
A40 R42 R44 P59 M66 K67 G70 P72 R74 R75 Y80 E106 T142 K169 H176 S177 V178 K182 P183
Binding residue
(residue number reindexed from 1)
A26 R28 R30 P45 M52 K53 G56 P58 R60 R61 Y66 E92 T93 K120 H127 S128 V129 K133 P134
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
GO:0003735
structural constituent of ribosome
GO:0042301
phosphate ion binding
Biological Process
GO:0000027
ribosomal large subunit assembly
GO:0002181
cytoplasmic translation
GO:0006412
translation
Cellular Component
GO:0000315
organellar large ribosomal subunit
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:8ova
,
PDBe:8ova
,
PDBj:8ova
PDBsum
8ova
PubMed
37985661
UniProt
Q389K1
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