Structure of PDB 8oiq Chain Bv Binding Site BS02

Receptor Information
>8oiq Chain Bv (length=238) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSPWRLLGALCLQRPPLVTKPLTPLQEEMADLLQQIEIERSLYSDHELRA
LDEAQQLAKKKSDLYEEEDEQNILLAQDLEDMWEQKFLHFKLGARLTEAD
KKDDRTSLHRKLDRNLILLVREKLGDQDIWMLPQSDWQPGETLRQTAERT
LATLSENNMEAKFLGNAPCGHYKFKFPQAMRTETSLGAKVFFFKALLLTG
DFSQAGKKGHHVWVSKEELGDYLKPKYLAQVRRFLLDL
Ligand information
Ligand IDPHE
InChIInChI=1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)/t8-/m0/s1
InChIKeyCOLNVLDHVKWLRT-QMMMGPOBSA-N
SMILES
SoftwareSMILES
CACTVS 3.341N[CH](Cc1ccccc1)C(O)=O
CACTVS 3.341N[C@@H](Cc1ccccc1)C(O)=O
OpenEye OEToolkits 1.5.0c1ccc(cc1)CC(C(=O)O)N
OpenEye OEToolkits 1.5.0c1ccc(cc1)C[C@@H](C(=O)O)N
ACDLabs 10.04O=C(O)C(N)Cc1ccccc1
FormulaC9 H11 N O2
NamePHENYLALANINE
ChEMBLCHEMBL301523
DrugBankDB00120
ZINCZINC000000105196
PDB chain8oiq Chain B9 Residue 101 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8oiq Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		L165 G166 F217
Binding residue
(residue number reindexed from 1)		L124 G125 F176
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0030054 cell junction
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB RCSB:8oiq, PDBe:8oiq, PDBj:8oiq
PDBsum8oiq
PubMed37141370
UniProtF1SRT0

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