Structure of PDB 7o7z Chain Bj Binding Site BS02

Receptor Information

>7o7z Chain Bj (length=86) Species: 9986 (Oryctolagus cuniculus)

TKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSA
KAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPK

Ligand information

>7o7z Chain B8 (length=156)

cgacucuuagcgguggaucacucggcucgugcgucgaugaagaacgcagc
uagcugcgagaauuaaugugaauugcaggacacauugaucaucgacacuu
cgaacgcacuugcggccccggguuccucccggggcuacgccugucugagc
gucgcu

.........................................<<<<<<<<<
....>>>>.....<.<<<......>>.............>>>..>...>>
>....<<....>><<<<<<<<<.....>>>>>>>>>..............
......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 7o7z Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): R20 R21 C22 G23 Y39 K42 N57 T59 G60 G62 R63 M64 R65 H66 L67 K68 R72 F74 H76 R79 E80 G81 T82 T83 P84 K85 K87
• Binding residue (residue number reindexed from 1): R19 R20 C21 G22 Y38 K41 N56 T58 G59 G61 R62 M63 R64 H65 L66 K67 R71 F73 H75 R78 E79 G80 T81 T82 P83 K84 K86

Gene Ontology

Molecular Function

• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding
• GO:0046872 metal ion binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:7o7z, PDBe:7o7z, PDBj:7o7z
• PDBsum: 7o7z
• PubMed: 34029205
• UniProt: U3KPD5|RL37_RABIT Large ribosomal subunit protein eL37 (Gene Name=RPL37)