Structure of PDB 8oit Chain Bh Binding Site BS02

Receptor Information
>8oit Chain Bh (length=162) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FREVVETQEGKTTIIEGRITATPKESPNPPNPSGQCPICRWNLKHKYNYD
DVLLLSQFIRPHGGMLPRKITGLCQEEHRKIEECVKMAHRAGLLPNHRPR
LPEGVVPKSKPQLNRYLTRWAPGSVKPIYKKGPRWNRVRMPVGSPLLRDN
VCYSRTPWKLYH
Ligand information
Ligand IDFS2
InChIInChI=1S/4Fe.3O.2S
InChIKeyDEAINXNPDRNZAH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 2.0.7O1[Fe]O2[Fe]134O[Fe]356[S]4[Fe]52S6
CACTVS 3.385O1[Fe]O[Fe]1O[Fe]2S[Fe]S2
FormulaFe4 O3 S2
NameFE-S-O HYBRID CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain8oit Chain Bh Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB8oit Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		C70 C73 K78 C108 E111
Binding residue
(residue number reindexed from 1)		C36 C39 K44 C74 E77
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0070181 small ribosomal subunit rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oit, PDBe:8oit, PDBj:8oit
PDBsum8oit
PubMed37141370
UniProtQ9NVS2|RT18A_HUMAN Large ribosomal subunit protein mL66 (Gene Name=MRPS18A)

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