Structure of PDB 7lh5 Chain BS Binding Site BS02
Receptor Information
>7lh5 Chain BS (length=102) Species:
300852
(Thermus thermophilus HB8) [
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YERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSASSLAL
KLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALAEGAR
EG
Ligand information
>7lh5 Chain BB (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
7lh5
Structural basis for plazomicin antibiotic action and resistance.
Resolution
3.27 Å
Binding residue
(original residue number in PDB)
R17 R25 F29 S31 L32 K33 Y36 Q38 G45 V46 T47 L54 G60 N61 K62 T63 K93 H95
Binding residue
(residue number reindexed from 1)
R11 R19 F23 S25 L26 K27 Y30 Q32 G39 V40 T41 L48 G54 N55 K56 T57 K87 H89
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
GO:0008097
5S rRNA binding
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:7lh5
,
PDBe:7lh5
,
PDBj:7lh5
PDBsum
7lh5
PubMed
34117352
UniProt
Q5SHQ4
|RL18_THET8 Large ribosomal subunit protein uL18 (Gene Name=rplR)
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