Structure of PDB 4v9r Chain BS Binding Site BS02
Receptor Information
>4v9r Chain BS (length=110) Species:
274
(Thermus thermophilus) [
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RLTAYERRKFRVRNRIKRTGRLRLSVFRSLKHIYAQIIDDEKGVTLVSAS
SLALKLKGNKTEVARQVGRALAEKALALGIKQVAFDRGPYKYHGRVKALA
EGAREGGLEF
Ligand information
>4v9r Chain BB (length=120) [
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ucccccgugcccauagcggcguggaaccacccguucccauuccgaacacg
gaagugaaacgcgccagcgccgaugguacugggcgggcgaccgccuggga
gaguaggucggugcggggga
<<<<<<<<<<<....<<<<<<<<....<<<<<<...............>>
>..>>>...>>>>>>.>><<<.......<<<<<<<<....>>>>>>>>..
.....>>>.>>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
4v9r
The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
R15 R25 F29 R30 S31 L32 H34 Y36 Q38 G45 V46 T47 S50 L54 N61 K62 T63 Y92 K93 H95 G96 R97
Binding residue
(residue number reindexed from 1)
R13 R23 F27 R28 S29 L30 H32 Y34 Q36 G43 V44 T45 S48 L52 N59 K60 T61 Y90 K91 H93 G94 R95
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003735
structural constituent of ribosome
GO:0008097
5S rRNA binding
GO:0019843
rRNA binding
Biological Process
GO:0006412
translation
Cellular Component
GO:0005737
cytoplasm
GO:0005840
ribosome
GO:0022625
cytosolic large ribosomal subunit
GO:1990904
ribonucleoprotein complex
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Cellular Component
External links
PDB
RCSB:4v9r
,
PDBe:4v9r
,
PDBj:4v9r
PDBsum
4v9r
PubMed
24412368
UniProt
Q5SHQ4
|RL18_THET8 Large ribosomal subunit protein uL18 (Gene Name=rplR)
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