Structure of PDB 5aj4 Chain BQ Binding Site BS02

Receptor Information
>5aj4 Chain BQ (length=221) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KTLLPVPTFEDVAIPEKPKLRFVERVPLVPKVRRERKNLSDIRGPSTEAT
EFTEGRFAILALGGGYLHWGHFEMMRLTINRSMDPKNMFALWRVPAPFKP
ITRKGMGQRMGGGKGAIDHYVTPVKAGRLIVEMGGRCEFKEVQGFLDLVA
HKLPFPAKAVSRETLEKMRKDQEERERNNQNPWTFERIATANMLGIRKVL
SPYDLTHKGRYWGKFYTPERV
Ligand information
>5aj4 Chain BA (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacaacaaauacaaaaauacaccaaaauaaaauaaa
acauucaccuaacauuaaaguauaggagauagaaauuuuuauccugacgc
uauagagauaguaccguaagggaaagaugaaagaauaaaaguaaaaaaaa
gcaaagauuaccccuucuaccuuuugcauaaugguuuaaccagaaaaaau
cuaacaaagagaacuuuagcuagauaccccgaaaccagacgagcuaccca
ugagcaguuuaaaagaaccaacucaucuauguggcaaaauagugagaaga
cuuguagguagaggugaaaagccuaacgagccuggugauagcugguuguc
cgagaaagaauuuuaguucaaccuuaaaaauaccccaaaaacccuaaauu
ccaauguauuuuuaagagauagucuaaaaagguacagcuuuuuagaaacg
gauacaaccuugacuagagaguaaaucuuaauacuaccauaguaggccua
aaagcagccaucaauugagaaagcguuaaagcucaacaaauucaccaaca
uaaucccaaaaacuaauaacaaacuccuagcccaauaccggacuaaucua
uugaaacauagaagcaauaauguuaauaugaguaacaagaagccuuucuc
cucgcacacgcuuacaucaguaacuaauaauauacugauaauuaacaacc
aauaaaccaaaacaacacuaaaacguuuauuaauuacauuguuaacccaa
cacaggagugcaccaaggaaagauuaaaagaaguaaaaggaacucggcaa
acacaaaccccgccuguuuaccaaaaacaucaccucuagcauuacuagua
uuagaggcaaugccugcccagugacaaguuuaacggccgcgguacugacc
gugcaaagguagcauaaucacuuguucuccaaauaaggacuuguaugaau
ggccacacgaggguuuuacugucucuuacuuccaaucagugaaauuaacc
uucccgugaagaggcgggaauaaaaaaauaagacgagaagacccuaugga
gcuuuaauuaacuauuccaaaaguucuuaacauggacuagcaauuucggu
uggggugaccucggaguacaaaaaacccuccgagugauuuuaaucuagac
aaaccagucaaaauaaucacuuauugauccaaaauuuugaucaacggaac
aaguuacccuagggauaacagcgcaauccuguucuagaguuccuaucgac
aauaggguuuacgaccucgauguuggaucaggacacccaaauggugcagc
cgcuauuaaagguucguuuguucaacgauuaaaguccuacgugaucugag
uucagaccggagcaauccaggucgguuucuaucuauuauaaauuucuccc
aguacgaaaggacaagagaaaugggaccaaccucacaaacgcgucucaga
gauaauuaaugauuuaaucuuaaccuaauuaacucauaauaaauccagcc
cuagaacagggcaca
<<........<<<<.................................<..
....>.................<<.....>>..............>>.>>
.............<<....>>...................>>........
...<<<.......>>>...<.<........>.>..<<<<<........<<
<<<.<..<<....>>...>.>>>>>..<<.<..<<<<<.<.....<<<.<
<<<<..<<<......>>>...<<<<.<<<<........>>>>>>>>....
>>>>>.>>>...<<<.....>>>......>.>>>>...>..>.>>..<<<
<<.....<<<<....>>>>...<<<<<<<<<<<.....<<........>>
.....>>>>>>>>>>>......<<<<<<<<<......>>>>>>>>>...<
<......>>....<<<<.<<<..................<....<<<...
......>>>....>.......<<<......>>>.................
.......................>>>>>>>........>>>>>...<<<<
<......>>>>>.........>>>>>.<......<<..<<<<..>>>><<
<<.<<<<........<<<<<....<<....>>..>>>>>......<<<..
<<<<<<<.................>>>>>>>.......>>>.....<<..
....>>.>>>>....>>>>..<<<<....<<<<<<<.<<...........
....<<<<<<<<..<<<.........>>>...<<<<<<............
.>>>>>>...<<<<.<<<..<<<<<..>>>..>>>>><<<<<<....>>>
>>>........<...........<<<<<.......>>>>>.....>....
>>>.>..>>.>>>>>>......>>.>>>>>>>.>>>>.>>.....>..(.
.<<<<<.......)>>>>>.......<<<.<<<.<<......<<<<.<<<
<<<..<<<<..<<<.<<<<.<<<..>>>....>>>>.>>>.>>>>..<<<
<.....>>>><<<<<<...........>>>>>>.<<<<....<<...<<<
......>>>...>>.>>>>..........<<<<..>>>>...........
.>>>>..>>>>>>.......<<<..<.<<<<<<...<<.......>>...
>>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<<.....
.>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>
....<<<<<<<....>>>.>>>>....>>..>>>>>>.<<.<<<<<<<..
...............>>>>>>><<<<<...............>>>>>.<<
<...<<<<.................>>>>...>>>.>>.........<<<
<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5aj4 The complete structure of the 55S mammalian mitochondrial ribosome.
Resolution3.8 Å
Binding residue
(original residue number in PDB)		K31 R63 R64 R66 K67 L69 R73 H101 M104 R111 R133 M136 G137 Q138 R139 M140 G141 G142 G143 K144 H181 K182 P184 R227 K228 V229 S231 P232 Y233
Binding residue
(residue number reindexed from 1)		K1 R33 R34 R36 K37 L39 R43 H71 M74 R81 R103 M106 G107 Q108 R109 M110 G111 G112 G113 K114 H151 K152 P154 R197 K198 V199 S201 P202 Y203
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5aj4, PDBe:5aj4, PDBj:5aj4
PDBsum5aj4
PubMed25837512
UniProtF1RI89

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