Structure of PDB 4v78 Chain BO Binding Site BS02

Receptor Information

>4v78 Chain BO (length=116) Species: 83333 (Escherichia coli K-12)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>4v78 Chain BB (length=117)

gccuggcggccguagcgcgguggucccaccugaccccaugccgaacucag
aagugaaacgccguagcgccgaugguaguguggggucuccccaugcgaga
guagggaacugccaggc

<<<<<<<<......<<<<<<<<....<<<<<<<.............>>>>
..>>>...>>>>>>.>>.<<.....<.<<<<<<<<...>>>>>>>>...>
...>>....>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v78 Energy barriers and driving forces in tRNA translocation through the ribosome.
• Resolution: 20.0 Å
• Binding residue (original residue number in PDB): D2 K3 K4 P32 R33 G44 K63 Y64 N67 K68 Q98 H100 G101 R102
• Binding residue (residue number reindexed from 1): D1 K2 K3 P31 R32 G43 K62 Y63 N66 K67 Q97 H99 G100 R101

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v78, PDBe:4v78, PDBj:4v78
• PDBsum: 4v78
• PubMed: 24186064
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)