Structure of PDB 4v76 Chain BO Binding Site BS02

Receptor Information

>4v76 Chain BO (length=116) Species: 83333 (Escherichia coli K-12)

DKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNGSEVLVAA
STVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHG
RVQALADAAREAGLQF

Ligand information

>4v76 Chain BB (length=117)

gccuggcggccguagcgcgguggucccaccugaccccaugccgaacucag
aagugaaacgccguagcgccgaugguaguguggggucuccccaugcgaga
guagggaacugccaggc

<<<<<<<<<.....<<<<<<<<....<<<<<<<.............>>>>
..>>>...>>>>>>.>>.<<.......<<<<<<<<...>>>>>>>>....
...>>...>>>>>>>>>

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v76 Energy barriers and driving forces in tRNA translocation through the ribosome.
• Resolution: 17.0 Å
• Binding residue (original residue number in PDB): K3 R25 H29 P32 R33 H34 Y36 Q38 I40 G44 S45 E46 V47 V54 K56 Y64 K68 G101
• Binding residue (residue number reindexed from 1): K2 R24 H28 P31 R32 H33 Y35 Q37 I39 G43 S44 E45 V46 V53 K55 Y63 K67 G100

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0008097 5S rRNA binding
• GO:0019843 rRNA binding

Biological Process

• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Cellular Component

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0005840 ribosome
• GO:0022625 cytosolic large ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:4v76, PDBe:4v76, PDBj:4v76
• PDBsum: 4v76
• PubMed: 24186064
• UniProt: P0C018|RL18_ECOLI Large ribosomal subunit protein uL18 (Gene Name=rplR)